Generating Survival Times Using Cox Proportional Hazards Models with Cyclic and Piecewise Time-Varying Covariates
نویسندگان
چکیده
منابع مشابه
Generating survival times to simulate Cox proportional hazards models with time-varying covariates
Simulation studies present an important statistical tool to investigate the performance, properties and adequacy of statistical models in pre-specified situations. One of the most important statistical models in medical research is the proportional hazards model of Cox. In this paper, techniques to generate survival times for simulation studies regarding Cox proportional hazards models are pres...
متن کاملGenerating Survival Times to Simulate Cox Proportional Hazards Models
Number of words: 2795 (excluding summary, references and tables) 2 SUMMARY This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression coefficients and the simulated random errors. Thus, the response variable can...
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The Cox proportional-hazards regression model has achieved widespread use in the analysis of time-to-event data with censoring and covariates. The covariates may change their values over time. This article discusses the use of such time-dependent covariates, which offer additional opportunities but must be used with caution. The interrelationships between the outcome and variable over time can ...
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Background: Thalassemia major (TM) is a severe disease and the most common anemia worldwide. The survival time of the disease and its risk factors are of importance for physicians. The present study was conducted to apply the semi-parametric Cox PH model and use parametric proportional hazards (PH) and accelerated failure time (AFT) models to identify the risk factors related to survival of TM ...
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ژورنال
عنوان ژورنال: Statistics in Biosciences
سال: 2020
ISSN: 1867-1764,1867-1772
DOI: 10.1007/s12561-020-09266-3